Frequently Asked
Questions

You have questions? We have answers.

Product

What is Nuceiva (Botulinum Toxin Type A) for?

NUCEIVA is indicated for the temporary improvement in the appearance of moderate to severe vertical lines between the eyebrows seen at maximum frown (glabellar lines), when the severity of the above facial lines has an important psychological impact in adults below 65 years of age.1

How do I reconstitute Nuceiva?

Please first refer to Section 6.6 of the Nuceiva Summary of Product Characteristics. NUCEIVA should only be administered by healthcare practitioners with appropriate qualifications and expertise in the treatment of glabellar lines and the use of required equipment.

Can you please provide more information on the product manufacturing?

Nuceiva is manufactured in South Korea.

NUCEIVA should only be administered by healthcare practitioners with appropriate qualifications and expertise in the treatment of glabellar lines and the use of required equipment.

What is Hi-Pure technology?

Hi-Pure Technology is our patented manufacturing process2.

For more information - ask your multichannel manage. For more information – contact us here.

2. Patentsgoogle. Daewong Method for production of botulinum toxin. Last reviewed 2022. patents.google.com/patent/US9512418B2/en (Accessed:11/23)

How long will Nuceiva last?

Nuceiva lasts up to 4 months.1

Nuceiva® injections significantly reduced the severity of glabellar lines by 1 point or greater at maximum frown for up to 139 days, as measured by the investigator assessment of glabellar line severity at maximum frown.

How long before the onset of action?

Nuceiva acts in 2 days1

At day 2, the percentages of responders in each of the Nuceiva®, Botox® and placebo groups were 54.2%, 57.0%, and 12.2%, respectively. The test of superiority of Nuceiva® vs placebo was highly statistically significant: the absolute difference in the percentages of responders was 41.9% (P < 0.001)

How do I inject Nuceiva?

Please first refer to the Nuceiva Summary of Product Characteristics for administration contraindications, precautions, warnings and instructions. NUCEIVA should only be administered by healthcare practitioners with appropriate qualifications and expertise in the treatment of glabellar lines and the use of required equipment.

Patient

Do you have any resources that can support me with my consultation?

Please speak to your MCM for more information.

Training

Do you offer training?

We offer training to support the use of our product. We also hold regular online and in person events. To express interest in upcoming face to face events click here.

I want to learn from a KOL who injects Nuceiva

We have relationships with Key Opinion Leaders, in both the United States & Europe, who inject suitable patients with Nuceiva and educate other HCPs on injection technique. For more information on KOL training please contact our MCM team here.

I am new to the industry - can you suggest any courses I should do?

Welcome to Aesthetics! There are many courses available for those looking to get into the industry. These are mostly offered by schools, KOL's or independent operators. We don't have a vendor that we endorse. If you have any questions about our product - please don't hesitate to get in touch with one of our MultiChannel Managers. You'll be able to book a call here.

I've been in the industry for a long time - what is the value in learning about treatment of the glabella?

Do you know the 5 glabellar types? The glabellar is one of the most complex facial muscular structures. In recognition of this complexity and the need for precise injection technique, we have some focused training available. Please register here.

General

Evolus says they are a performance beauty company - what does that mean?

Evolus is a performance beauty company - in the words of David Moatazedi, our CEO: we've taken lessons from the beauty industry such as reacting to trends and understanding the consumer a little better, and applied them to pharmaceutical performance standards.

I am unhappy with the service I've received - who do I speak to?

We are so sorry to hear that. Please book a conversation with us here. We will do our best to help.

I am very happy with the service I've received - how can I pass on kudos?

Thank you for wanting to give kudos! Our team work very hard, and they love the aesthetic industry. You can send as an email here and we will make sure the team member you're impressed with is rewarded.

When will Nuceiva be available across Europe?

Nuceiva is licensed in 35 countries. If you have specific questions about how you can access Nuceiva in specific countries - please speak to your MCM.

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Adverse events should be reported

Reporting forms and information can be found at yellowcard.mhra.gov.uk/ or search MHRA yellow card in the Google Play or Apple App Store.

Adverse events should also be reported to Evolus International Ltd.

Please contact Evolus Europe Medical Information by medicalinformation@evolus.com or calling 08000541302.

Evolus clinical trial details can be found here. For any additional information, please email medicalinformation@evolus.com

Evolus is unable to provide advice on personal medical matters. Please consult your healthcare professional for specific, health-related advice and support.Links to the electronic medicines compendium (emc) website to access the Patient Information Leaflets (PIL) and Summary of Product Characteristics (SmPC) for our medicine in the United Kingdom is also available here.

NUCEIVA PRESCRIBING INFORMATION

Legal category: POM. List price: 50 unit vial - £75.50

REPORTING OF SIDE EFFECTS FOR THE UNITED KINGDOM

Adverse events should be reported.Reporting forms and information can be found at yellowcard.mhra.gov.uk/ or search MHRA yellow card in the Google Play or Apple App Store.

Adverse events should also be reported to Evolus International Ltd.

Please contact Evolus Europe Medical Information by medicalinformation@evolus.com or calling 08000541302.

By selecting the healthcare professional option, you confirm you are a healthcare professional and acknowledge that you will be exposed to promotional information relating to prescription only medicines.

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